Moxitak-PD (Eye Drops)

“WHEN INFECTION AND INFLAMMATION CO-EXIST”

Composition:

Moxifloxacin hydrochloride eq. to moxifloxacin 0.5%,Prednisolone Acetate 1.0%, Benzalkonium Chloride Solution 0.02% (As preservative), Sterile aqueous vehicle q.s.

Pharmacology

Mode of Action: MOXITAK-PD constitutes 4^th generation Fluoro-Quinolones, Moxifloxacin as an anti-bacterial agent. Floro-Quinolones exert their antibacterial effect by preventing bacterial DNA from unwinding and duplicating. Moxifloxacin hydrochloride is a synthetic 8-methoxyfluoroquinolone with a broad spectrum anti-bacterial effect on gram positive, gram negative and other anaerobic micro-organism. PREDNISOLONE is a corticosteroid drug with predominant glucocorticoid and low mineralocorticoid activity, making it useful for the treatment of a wide range of inflammatory and used to reduce swelling, redness, itching, and allergic reactions affecting the eye. Corticosteroids inhibit the inflammatory response to a variety of inciting agents and, it is presumed, delay or slow healing. Thus inhibits the edema, fibrin deposition, capillary dilation, leukocyte migration, capillary proliferation, fibroblast proliferation, deposition of collagen, and scar formation with inflammation

Indication and Usage

Post operative inflammations and ocular inflammation related to bacterial infections from the below mentioned strains:

Corynebacterium species
- Micrococcus luteus
- Staphylococcus aureus
- Staphylococcus epidermidis
- Staphylococcus haemolyticus
- Staphylococcus hominis
- Haemophilus parainfluenzae
- Staphylococcus warneri
- Streptococcus pneumoniae
- Streptococcus viridans group
- Acinetobacter Iwoffii
- Haemophilus influenzae
- Chlamydia trachomatis

Dosage and Administration

Instill one or two drops in the eye for 2-3 times a day or as directed by the physician

Warning and Precaution

Warnings:

Growth of Resistant Organisms with Prolonged Use
Avoidance of Contact Lens Wear
if irritations persist, discontinue the use and consult the eye doctor
Delays Healing
Should not be administered in eyes with herpes simplex and fungal infection
Corticosteroids should not be indicated in corneal ulcers.
Prolonged use may cause glaucoma or cataract.

Adverse Effect: Stinging Sensation on instillation, blurry vision, allergic reaction, Irritation in the eye and watery eyes.