Mode of Action: OFLOXACIN is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone. Ofloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative aerobic bacteria. It functions by inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase IV, which is an enzyme necessary to separate, replicated DNA and also help in its repair, thereby inhibiting bacterial cell division.

For Eye: Treat Infections caused in the conditions of Bacterial conjunctivitis, Bacterial Corneal Ulcers, Bacterial Keratitis, blepharitis, stye due to the susceptible strains mentioned below. For Ear: Infection caused due to the below mentioned strains arises conditions of Otitis Externa and Media Acute Otitis.

Aerobic Gram-Negative	Anaerobic Species	Aerobic Gram-Positive:
Escherichia coli	Propionibacterium acnes	Streptococcus pneumoniae
Enterobacter cloacae		Staphylococcus epidermidis
Haemophilus influenza		Staphylococcus aureus
Pseudomonas aeruginosa
Serratia marcescens
Moraxella catarrhalis

Apply thin strip (about 1 cm) of ointment into the affected eye(s) every 4 hours or as directed by physician. Adverse Effect: Transient ocular burning or discomfort, stinging, itching, redness, tearing, and dryness may occur. Allergic reactions, facial edema, blurred vision and eye pain may also occur.